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mdapca 2b  (ATCC)


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    ATCC mdapca 2b
    Mdapca 2b, supplied by ATCC, used in various techniques. Bioz Stars score: 96/100, based on 314 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/mdapca+2b/MDA+PCa+2b/10__1158_slash_2767___9764__crc___25___0254-59-8-15
    Average 96 stars, based on 314 article reviews
    mdapca 2b - by Bioz Stars, 2026-10
    96/100 stars

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    other:

    Article Title: Modulation of TGFβ-inducible hypermotility by EGF and other factors in human prostate epithelial cells and keratinocytes
    Article Snippet: Human prostate carcinoma cell lines PC3 [ Kaighn et al., 1979 ], MDAPCa-2b [ Rajagopal et al., 1998 ], and LNCaP [ Horoszewicz et al., 1983 ], obtained from the American Type Culture Collection by the Harvard Skin Disease Research Center, were grown in DMEM/F12 medium (GIBCO) supplemented with 10% newborn calf serum (Hyclone, Logan, UT).

    Article Title: Docetaxel down-regulates the expression of androgen receptor and prostate-specific antigen but not prostate-specific membrane antigen in prostate cancer cell lines: implications for PSA surrogacy.
    Article Snippet: BACKGROUND.. Docetaxel (DOC) has potent anti-tumor efficacy as a result of promoting microtubule assembly and microtubule bundling thereby impairing mitosis.. Knowing that some anti-microtubule agents affect the polarity of prostate-specific membrane antigen (PSMA) expression and that androgen ablation can up-regulate PSMA expression, we sought to determine any effect of DOC on PSMA expression in prostate cancer (PC) cell lines as a prelude to a clinical effort.

    Article Title: Novel Afro-Caribbean Prostate Cancer Model Reveals ancestry-specific Drug Vulnerabilities with Therapeutic Implications for Black Patients
    Article Snippet: Commercial cell lines DU-145 (RRID:CVCL_0105), PC-3 (RRID:CVCL_0035), and MDAPCA-2b (RRID:CVCL_4748) were purchased directly from the American Type Culture Collection (ATCC, Manassas, VA; RRID:SCR_001672) with authentication certificates and mycoplasma-free certification.

    Derivative Assay:

    Article Title: Genome-wide differentially methylated genes in prostate cancer tissues from African-American and Caucasian men.
    Article Snippet: .. The androgen-dependent PCa cell line, E006AA, and androgen-independent cell line, MDAPCa-2b, were derived from AA PCa patients and obtained from ATCC, respectively. .. All cell lines were maintained in RPMI supplemented with 10% fetal bovine serum (Invitrogen, Carlsbad, CA), unless stated otherwise.



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